Diamminetetrakis(carboxylato)platinum(IV) Complexes – Synthesis, Characterization, and Cytotoxicity

A series of eight novel diamminetetrakis(carboxylato)platinum(IV) complexes was synthesized and characterized by multinuclear (1)H-, (13)C-, (15)N-, and (195)Pt-NMR spectroscopy. Their antiproliferative potency was evaluated in three human cancer cell lines representing ovarian (CH1), lung (A549), a...

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Detalhes bibliográficos
Main Authors: Hoffmeister, Björn R, Adib-Razavi, Mahsa S, Jakupec, Michael A, Galanski, Markus, Keppler, Bernhard K
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
Assuntos:
Medicinal Bioinorganic Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499686/
https://ncbi.nlm.nih.gov/pubmed/22976974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbdv.201200019
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