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Unsymmetric Mono- and Dinuclear Platinum(IV) Complexes Featuring an Ethylene Glycol Moiety: Synthesis, Characterization, and Biological Activity

Eight novel mononuclear and two dinuclear platinum(IV) complexes were synthesized and characterized by elemental analysis, one- and two-dimensional NMR spectroscopy, mass spectrometry, and reversed-phase HPLC (log k(w)) and in one case by X-ray diffraction. Cytotoxicity of the compounds was studied...

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書誌詳細
主要な著者: Pichler, Verena, Heffeter, Petra, Valiahdi, Seied M., Kowol, Christian R., Egger, Alexander, Berger, Walter, Jakupec, Michael A., Galanski, Markus, Keppler, Bernhard K.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021451/
https://ncbi.nlm.nih.gov/pubmed/23194425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301645g
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