Comparative studies of oxaliplatin-based platinum(iv) complexes in different in vitro and in vivo tumor models†

Using platinum(iv) prodrugs of clinically established platinum(ii) compounds is a strategy to overcome side effects and acquired resistances. We studied four oxaliplatin-derived platinum(iv) complexes with varying axial ligands in various in vitro and in vivo settings. The ability to interfere with...

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Detalhes bibliográficos
Publicado no:Metallomics
Main Authors: Göschl, Simone, Schreiber-Brynzak, Ekaterina, Pichler, Verena, Cseh, Klaudia, Heffeter, Petra, Jungwirth, Ute, Jakupec, Michael A., Berger, Walter, Keppler, Bernhard K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130776/
https://ncbi.nlm.nih.gov/pubmed/28205649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6mt00226a
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