JAK1-mediated Sirt1 phosphorylation functions as a negative feedback of the JAK1-STAT3 pathway

The type III NAD–dependent histone deacetylase Sirt1 plays important roles in a variety of pathobiological functions through targeting either the acetylated histones or transcription factors. However, the molecular mechanisms underlying how the Sirt1 functions are regulated remain vague. Herein we i...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Wang, Wenhui, Li, Fei, Xu, Yuanming, Wei, Juncheng, Zhang, Yana, Yang, Heeyoung, Gao, Beixue, Yu, Guohua, Fang, Deyu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052220/
https://ncbi.nlm.nih.gov/pubmed/29789426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001387
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker