Protein Inhibitor of Activated STAT (PIAS) Negatively Regulates the JAK/STAT Pathway by Inhibiting STAT Phosphorylation and Translocation

Protein inhibitor of activated STAT (PIAS) proteins are activation-suppressing proteins for signal transducer and activator of transcription (STAT), which involves gene transcriptional regulation. The inhibitory mechanism of PIAS proteins in the Janus kinase (JAK)/STAT signaling pathway has been wel...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Niu, Guo-Juan, Xu, Ji-Dong, Yuan, Wen-Jie, Sun, Jie-Jie, Yang, Ming-Chong, He, Zhong-Hua, Zhao, Xiao-Fan, Wang, Jin-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212522/
https://ncbi.nlm.nih.gov/pubmed/30416501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02392
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