SIRT1 is regulated by a PPARγ–SIRT1 negative feedback loop associated with senescence

Human Silent Information Regulator Type 1 (SIRT1) is an NAD(+)-dependent deacetylase protein which is an intermediary of cellular metabolism in gene silencing and aging. SIRT1 has been extensively investigated and shown to delay senescence; however, less is known about the regulation of SIRT1 during...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Han, Limin, Zhou, Rui, Niu, Jing, McNutt, Michael A., Wang, Pan, Tong, Tanjun
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995042/
https://ncbi.nlm.nih.gov/pubmed/20660480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq609
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares