A Peroxisome Proliferator-activated Receptor γ (PPARγ)/PPARγ Coactivator 1β Autoregulatory Loop in Adipocyte Mitochondrial Function

Peroxisome proliferator-activated receptor γ (PPARγ) activation induces adipogenesis and also enhances lipogenesis, mitochondrial activity, and insulin sensitivity in adipocytes. Whereas some studies implicate PPARγ coactivator 1α (PGC-1α) in the mitochondrial effect, the mechanisms involved in PPAR...

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Bibliographic Details
Main Authors: Deng, Tuo, Sieglaff, Douglas H., Zhang, Aijun, Lyon, Christopher J., Ayers, Steven D., Cvoro, Aleksandra, Gupte, Anisha A., Xia, Xuefeng, Baxter, John D., Webb, Paul, Hsueh, Willa A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162433/
https://ncbi.nlm.nih.gov/pubmed/21719705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251926
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