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Multiple Decisive Phosphorylation Sites for the Negative Feedback Regulation of SOS1 via ERK
EGF-induced activation of ERK has been extensively studied by both experimental and theoretical approaches. Here, we used a simulation model based mostly on experimentally determined parameters to study the ERK-mediated negative feedback regulation of the Ras guanine nucleotide exchange factor, son...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963383/ https://ncbi.nlm.nih.gov/pubmed/20724475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135517 |
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