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A Quantitative Model of ERK MAP Kinase Phosphorylation in Crowded Media

Cytoplasm contains a large number of macromolecules at extremely high densities. How this striking nature of intracellular milieu called macromolecular crowding affects intracellular signaling remains uncharacterized. Here, we examined the effect of macromolecular crowding on ERK MAPK phosphorylatio...

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Detalhes bibliográficos
Main Authors: Aoki, Kazuhiro, Takahashi, Koichi, Kaizu, Kazunari, Matsuda, Michiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607838/
https://ncbi.nlm.nih.gov/pubmed/23528948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01541
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