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Processive phosphorylation of ERK MAP kinase in mammalian cells
The mitogen-activated protein (MAP) kinase pathway is comprised of a three-tiered kinase cascade. The distributive kinetic mechanism of two-site MAP kinase phosphorylation inherently generates a nonlinear switch-like response. However, a linear graded response of MAP kinase has also been observed in...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150946/ https://ncbi.nlm.nih.gov/pubmed/21768338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104030108 |
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