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Development of an optimized backbone of FRET biosensors for kinases and GTPases

Biosensors based on the principle of Förster (or fluorescence) resonance energy transfer (FRET) have shed new light on the spatiotemporal dynamics of signaling molecules. Among them, intramolecular FRET biosensors have been increasingly used due to their high sensitivity and user-friendliness. Time-...

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Detalhes bibliográficos
Main Authors: Komatsu, Naoki, Aoki, Kazuhiro, Yamada, Masashi, Yukinaga, Hiroko, Fujita, Yoshihisa, Kamioka, Yuji, Matsuda, Michiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226481/
https://ncbi.nlm.nih.gov/pubmed/21976697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-01-0072
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