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Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin
Extracellular signal-regulated kinase (ERK) is a key effector of many growth signalling pathways. In this study, we visualise epidermal ERK activity in living mice using an ERK FRET biosensor. Under steady-state conditions, the epidermis occasionally revealed bursts of ERK activation patterns where...
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| Publicado en: | eLife |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337632/ https://ncbi.nlm.nih.gov/pubmed/25668746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05178 |
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