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Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin

Extracellular signal-regulated kinase (ERK) is a key effector of many growth signalling pathways. In this study, we visualise epidermal ERK activity in living mice using an ERK FRET biosensor. Under steady-state conditions, the epidermis occasionally revealed bursts of ERK activation patterns where...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Hiratsuka, Toru, Fujita, Yoshihisa, Naoki, Honda, Aoki, Kazuhiro, Kamioka, Yuji, Matsuda, Michiyuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337632/
https://ncbi.nlm.nih.gov/pubmed/25668746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05178
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