The Scaffold Protein Shoc2/SUR-8 Accelerates the Interaction of Ras and Raf

Shoc2/SUR-8 positively regulates Ras/ERK MAP kinase signaling by serving as a scaffold for Ras and Raf. Here, we examined the role of Shoc2 in the spatio-temporal regulation of Ras by using a fluorescence resonance energy transfer (FRET)-based biosensor, together with computational modeling. In epid...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Matsunaga-Udagawa, Rie, Fujita, Yoshihisa, Yoshiki, Sayaka, Terai, Kenta, Kamioka, Yuji, Kiyokawa, Etsuko, Yugi, Katsuyuki, Aoki, Kazuhiro, Matsuda, Michiyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844225/
https://ncbi.nlm.nih.gov/pubmed/20051520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053975
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky