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The Scaffold Protein Shoc2/SUR-8 Accelerates the Interaction of Ras and Raf
Shoc2/SUR-8 positively regulates Ras/ERK MAP kinase signaling by serving as a scaffold for Ras and Raf. Here, we examined the role of Shoc2 in the spatio-temporal regulation of Ras by using a fluorescence resonance energy transfer (FRET)-based biosensor, together with computational modeling. In epid...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844225/ https://ncbi.nlm.nih.gov/pubmed/20051520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053975 |
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