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Activated Ras Protein Accelerates Cell Cycle Progression to Perturb Madin-Darby Canine Kidney Cystogenesis

In a number of human cancer cells, K-RAS is frequently mutated and activated constitutively, culminating in the induction of continuous cell growth, a hallmark of cancer cells. It is still unclear, however, how the mutated K-RAS induces morphological abnormalities in cancerous tissues. To investigat...

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Detalhes bibliográficos
Main Authors: Sakurai, Atsuro, Matsuda, Michiyuki, Kiyokawa, Etsuko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442505/
https://ncbi.nlm.nih.gov/pubmed/22829590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377804
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