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Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase
A key signalling molecule, c-Raf, is situated downstream from Ras and upstream from the mitogen-activated protein kinase kinase (MEK). We studied the mechanism underlying the signal transduction from Ras to MEK by using probes based on the principle of fluorescence resonance energy transfer. In agre...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1299259/ https://ncbi.nlm.nih.gov/pubmed/15711535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400349 |
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