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Distinct predictive performance of Rac1 and Cdc42 in cell migration

We propose a new computation-based approach for elucidating how signaling molecules are decoded in cell migration. In this approach, we performed FRET time-lapse imaging of Rac1 and Cdc42, members of Rho GTPases which are responsible for cell motility, and quantitatively identified the response func...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yamao, Masataka, Naoki, Honda, Kunida, Katsuyuki, Aoki, Kazuhiro, Matsuda, Michiyuki, Ishii, Shin
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669460/
https://ncbi.nlm.nih.gov/pubmed/26634649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17527
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