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Cdc42, Rac1, and Rac2 Display Distinct Patterns of Activation during Phagocytosis
The small G proteins Cdc42, Rac1, and Rac2 regulate the rearrangements of actin and membrane necessary for Fcγ receptor-mediated phagocytosis by macrophages. Activated, GTP-bound Cdc42, Rac1, and Rac2 bind to the p21-binding domain (PBD) of PAK1, and this interaction provided a basis for microscopic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC491814/ https://ncbi.nlm.nih.gov/pubmed/15169870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-11-0847 |
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