A Cdc42 Activation Cycle Coordinated by PI 3-Kinase during Fc Receptor-mediated Phagocytosis

Fcγ Receptor (FcR)-mediated phagocytosis by macrophages requires phosphatidylinositol 3-kinase (PI3K) and activation of the Rho-family GTPases Cdc42 and Rac1. Cdc42 is activated at the advancing edge of the phagocytic cup, where actin is concentrated, and is deactivated at the base of the cup. The t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Beemiller, Peter, Zhang, Youxin, Mohan, Suresh, Levinsohn, Erik, Gaeta, Isabella, Hoppe, Adam D., Swanson, Joel A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2010
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814791/
https://ncbi.nlm.nih.gov/pubmed/19955216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-05-0494
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