Multiple Decisive Phosphorylation Sites for the Negative Feedback Regulation of SOS1 via ERK

EGF-induced activation of ERK has been extensively studied by both experimental and theoretical approaches. Here, we used a simulation model based mostly on experimentally determined parameters to study the ERK-mediated negative feedback regulation of the Ras guanine nucleotide exchange factor, son...

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Bibliografiska uppgifter
Huvudupphovsmän: Kamioka, Yuji, Yasuda, Shuhei, Fujita, Yoshihisa, Aoki, Kazuhiro, Matsuda, Michiyuki
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963383/
https://ncbi.nlm.nih.gov/pubmed/20724475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135517
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