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A mutation-led search for novel functional domains in MeCP2
Most missense mutations causing Rett syndrome (RTT) affect domains of MeCP2 that have been shown to either bind methylated DNA or interact with a transcriptional co-repressor complex. Several mutations, however, including the C-terminal truncations that account for ∼10% of cases, fall outside these...
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| Yayımlandı: | Hum Mol Genet |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6030874/ https://ncbi.nlm.nih.gov/pubmed/29718204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy159 |
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