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New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy

Small molecules that deter the functions of DNA damage response machinery are postulated to be useful for enhancing the DNA damaging effects of chemotherapy or ionizing radiation treatments to combat cancer by impairing the proliferative capacity of rapidly dividing cells that accumulate replicative...

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Pubblicato in:Front Mol Biosci
Autori principali: Datta, Arindam, Brosh, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028597/
https://ncbi.nlm.nih.gov/pubmed/29998112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00059
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