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New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy

Small molecules that deter the functions of DNA damage response machinery are postulated to be useful for enhancing the DNA damaging effects of chemotherapy or ionizing radiation treatments to combat cancer by impairing the proliferative capacity of rapidly dividing cells that accumulate replicative...

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Publicat a:Front Mol Biosci
Autors principals: Datta, Arindam, Brosh, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028597/
https://ncbi.nlm.nih.gov/pubmed/29998112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00059
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