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Hitting the Bull’s Eye: Novel Directed Cancer Therapy Through Helicase-Targeted Synthetic Lethality
Designing strategies for anti-cancer therapy have posed a significant challenge. One approach has been to inhibit specific DNA repair proteins and their respective pathways to enhance chemotherapy and radiation therapy used to treat cancer patients. Synthetic lethality represents an approach that ex...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728353/ https://ncbi.nlm.nih.gov/pubmed/19173305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22048 |
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