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Synthetic Lethal Interactions of RECQ Helicases

DNA helicases have risen to the forefront as genome caretakers. Their prominent roles in chromosomal stability is demonstrated by the linkage of mutations in helicase genes to hereditary disorders with defects in DNA repair, the replication stress response, and/or transcriptional activation. Convers...

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Publicat a:Trends Cancer
Autors principals: Datta, Arindam, Dhar, Srijita, Awate, Sanket, Brosh, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855770/
https://ncbi.nlm.nih.gov/pubmed/33041245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2020.09.001
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