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Synthetic Lethal Interactions of RECQ Helicases

DNA helicases have risen to the forefront as genome caretakers. Their prominent roles in chromosomal stability is demonstrated by the linkage of mutations in helicase genes to hereditary disorders with defects in DNA repair, the replication stress response, and/or transcriptional activation. Convers...

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Bibliografiske detaljer
Udgivet i:Trends Cancer
Main Authors: Datta, Arindam, Dhar, Srijita, Awate, Sanket, Brosh, Robert M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855770/
https://ncbi.nlm.nih.gov/pubmed/33041245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2020.09.001
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