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Human premature aging, DNA repair and RecQ helicases

Genomic instability leads to mutations, cellular dysfunction and aberrant phenotypes at the tissue and organism levels. A number of mechanisms have evolved to cope with endogenous or exogenous stress to prevent chromosomal instability and maintain cellular homeostasis. DNA helicases play important r...

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Detalhes bibliográficos
Main Authors: Brosh, Robert M., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190726/
https://ncbi.nlm.nih.gov/pubmed/18006573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1008
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