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Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance

The RecQ helicases are guardians of the genome. Members of this conserved family of proteins have a key role in protecting and stabilizing the genome against deleterious changes. Deficiencies in RecQ helicases can lead to high levels of genomic instability and, in humans, to premature aging and incr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Bohr, Vilhelm A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606042/
https://ncbi.nlm.nih.gov/pubmed/18926708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2008.09.003
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