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Biochemical Characterization of the WRN-1 RecQ Helicase of Caenorhabditis elegans

The highly conserved RecQ helicases are essential for the maintenance of genomic stability. Werner syndrome protein, WRN, is one of five human RecQ helicase homologues, and a deficiency of the protein causes a hereditary premature aging disorder that is characterized by genomic instability. A WRN or...

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Detalhes bibliográficos
Main Authors: Hyun, Moonjung, Bohr, Vilhelm A., Ahn, Byungchan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583433/
https://ncbi.nlm.nih.gov/pubmed/18558712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800197m
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