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Biochemical Characterization of the WRN-1 RecQ Helicase of Caenorhabditis elegans

The highly conserved RecQ helicases are essential for the maintenance of genomic stability. Werner syndrome protein, WRN, is one of five human RecQ helicase homologues, and a deficiency of the protein causes a hereditary premature aging disorder that is characterized by genomic instability. A WRN or...

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Bibliografske podrobnosti
Main Authors: Hyun, Moonjung, Bohr, Vilhelm A., Ahn, Byungchan
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583433/
https://ncbi.nlm.nih.gov/pubmed/18558712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800197m
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