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Biochemical Characterization of the WRN-1 RecQ Helicase of Caenorhabditis elegans

The highly conserved RecQ helicases are essential for the maintenance of genomic stability. Werner syndrome protein, WRN, is one of five human RecQ helicase homologues, and a deficiency of the protein causes a hereditary premature aging disorder that is characterized by genomic instability. A WRN or...

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Détails bibliographiques
Auteurs principaux: Hyun, Moonjung, Bohr, Vilhelm A., Ahn, Byungchan
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583433/
https://ncbi.nlm.nih.gov/pubmed/18558712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800197m
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