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The role of RecQ helicases in non-homologous end-joining

DNA double-strand breaks are highly toxic DNA lesions that cause genomic instability, if not efficiently repaired. RecQ helicases are a family of highly conserved proteins that maintain genomic stability through their important roles in several DNA repair pathways, including DNA double-strand break...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Crit Rev Biochem Mol Biol
Hauptverfasser: Keijzers, Guido, Maynard, Scott, Shamanna, Raghavendra A., Rasmussen, Lene Juel, Croteau, Deborah L., Bohr, Vilhelm A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244233/
https://ncbi.nlm.nih.gov/pubmed/25048400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2014.942450
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