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RecQ helicases: suppressors of tumorigenesis and premature aging.

The RecQ helicases represent a subfamily of DNA helicases that are highly conserved in evolution. Loss of RecQ helicase function leads to a breakdown in the maintenance of genome integrity, in particular hyper-recombination. Germ-line defects in three of the five known human RecQ helicases give rise...

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Autores principales: Bachrati, Csanád Z, Hickson, Ian D
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223634/
https://ncbi.nlm.nih.gov/pubmed/12803543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030491
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