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RecQ helicases: suppressors of tumorigenesis and premature aging.
The RecQ helicases represent a subfamily of DNA helicases that are highly conserved in evolution. Loss of RecQ helicase function leads to a breakdown in the maintenance of genome integrity, in particular hyper-recombination. Germ-line defects in three of the five known human RecQ helicases give rise...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223634/ https://ncbi.nlm.nih.gov/pubmed/12803543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030491 |
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