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New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy

Small molecules that deter the functions of DNA damage response machinery are postulated to be useful for enhancing the DNA damaging effects of chemotherapy or ionizing radiation treatments to combat cancer by impairing the proliferative capacity of rapidly dividing cells that accumulate replicative...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Datta, Arindam, Brosh, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028597/
https://ncbi.nlm.nih.gov/pubmed/29998112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00059
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