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The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy

DNA helicases unwind or rearrange duplex DNA during replication, recombination and repair. Helicases of many pathogenic organisms such as viruses, bacteria, and protozoa have been studied as potential therapeutic targets to treat infectious diseases, and human DNA helicases as potential targets for...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Seo, Yeon-Soo, Kang, Young-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885281/
https://ncbi.nlm.nih.gov/pubmed/29651420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00026
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