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Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases

Tim (Timeless) and Tipin (Tim-interacting protein) form a stable heterodimeric complex that influences checkpoint responses and replication fork progression. We report that the Tim-Tipin complex interacts with essential replication fork proteins and affects their biochemical properties. The Tim-Tipi...

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Hlavní autoři: Cho, Won-Ho, Kang, Young-Hoon, An, Yun-Young, Tappin, Inger, Hurwitz, Jerard, Lee, Joon-Kyu
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574903/
https://ncbi.nlm.nih.gov/pubmed/23359676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222494110
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