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Bypass of a protein roadblock by a replicative DNA helicase
Replicative DNA helicases generally unwind DNA as a single hexamer that encircles and translocates along one strand of the duplex while excluding the complementary strand (“steric exclusion”). In contrast, large T antigen (T-ag), the replicative DNA helicase of the Simian Virus 40 (SV40), is reporte...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3521859/ https://ncbi.nlm.nih.gov/pubmed/23201686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11730 |
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