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Uncoupling of sister replisomes during eukaryotic DNA replication

The duplication of eukaryotic genomes involves the replication of DNA from up to several hundred thousand origins of replication. In S phase, two sister replisomes are assembled at each active origin, and they replicate DNA in opposite directions. Little is known about the functional relationship be...

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Bibliographic Details
Main Authors: Yardimci, Hasan, Loveland, Anna B., Habuchi, Satoshi, van Oijen, Antoine M., Walter, Johannes C.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004751/
https://ncbi.nlm.nih.gov/pubmed/21145490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.11.027
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