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The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy

DNA helicases unwind or rearrange duplex DNA during replication, recombination and repair. Helicases of many pathogenic organisms such as viruses, bacteria, and protozoa have been studied as potential therapeutic targets to treat infectious diseases, and human DNA helicases as potential targets for...

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Publicat a:Front Mol Biosci
Autors principals: Seo, Yeon-Soo, Kang, Young-Hoon
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885281/
https://ncbi.nlm.nih.gov/pubmed/29651420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00026
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