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New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy

Small molecules that deter the functions of DNA damage response machinery are postulated to be useful for enhancing the DNA damaging effects of chemotherapy or ionizing radiation treatments to combat cancer by impairing the proliferative capacity of rapidly dividing cells that accumulate replicative...

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Detalles Bibliográficos
Publicado en:Front Mol Biosci
Main Authors: Datta, Arindam, Brosh, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028597/
https://ncbi.nlm.nih.gov/pubmed/29998112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00059
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