Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors

Monoacylglycerol lipase is a serine hydrolase that plays a major role in the degradation of the endocannabinoid neurotransmitter 2-arachidonoylglycerol. A wide number of MAGL inhibitors are reported in literature; however, many of them are characterised by an irreversible mechanism of action and thi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Granchi, Carlotta, Caligiuri, Isabella, Bertelli, Eleonora, Poli, Giulio, Rizzolio, Flavio, Macchia, Marco, Martinelli, Adriano, Minutolo, Filippo, Tuccinardi, Tiziano
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009861/
https://ncbi.nlm.nih.gov/pubmed/28936880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1375484
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker