Actin polymerization contributes to enhanced pulmonary vasoconstrictor reactivity after chronic hypoxia

Chronic hypoxia (CH) augments basal and endothelin-1 (ET-1)-induced pulmonary vasoconstrictor reactivity through reactive oxygen species (ROS) generation and RhoA/Rho kinase (ROCK)-dependent myofilament Ca(2+) sensitization. Because ROCK promotes actin polymerization and the actin cytoskeleton regul...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Heart Circ Physiol
Egile Nagusiak: Weise-Cross, Laura, Sands, Michelle A., Sheak, Joshua R., Broughton, Brad R. S., Snow, Jessica B., Gonzalez Bosc, Laura V., Jernigan, Nikki L., Walker, Benjimen R., Resta, Thomas C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008138/
https://ncbi.nlm.nih.gov/pubmed/29373038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00664.2017
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