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High-Throughput Screening Approach for Identifying Compounds that Inhibit Non-Homologous End Joining
DNA double strand breaks (DSBs) are repaired primarily by homologous recombination (HR) or non-homologous end joining (NHEJ). Compounds that modulate HR have shown promise as cancer therapeutics. The V(D)J recombination reaction, which assembles antigen receptor genes in lymphocytes, is initiated by...
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| Izdano u: | SLAS Discov |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5997544/ https://ncbi.nlm.nih.gov/pubmed/29232168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217746324 |
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