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Aberrant V(D)J joining in ATM-deficient lymphocytes is dependent on non-homologous DNA end joining
During lymphocyte antigen receptor gene assembly, DNA cleavage by the Rag proteins generates pairs of coding and signal ends that are normally joined into coding joints and signal joints, respectively, by the classical non-homologous end-joining (NHEJ) pathway of DNA double strand break (DSB) repair...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3598579/ https://ncbi.nlm.nih.gov/pubmed/18684952 |
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