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Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes
Ataxia-telangiectasia mutated (ATM)–deficient lymphocytes exhibit defects in coding joint formation during V(D)J recombination in vitro. Similar defects in vivo should affect both T and B cell development, yet the lymphoid phenotypes of ATM deficiency are more pronounced in the T cell compartment. I...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118620/ https://ncbi.nlm.nih.gov/pubmed/17502661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061460 |
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