Redundant and Non-Redundant Functions of ATM and H2AX in αβ T-Lineage Lymphocytes

The Ataxia Telangiectasia mutated (ATM) kinase and H2AX histone tumor suppressor proteins are each critical for maintenance of cellular genomic stability and suppression of lymphomas harboring clonal translocations. ATM is the predominant kinase that phosphorylates H2AX in chromatin around DNA doubl...

Full description

Saved in:
Bibliographic Details
Main Authors: Yin, Bu, Lee, Baeck-Seung, Yang-Iott, Katherine S., Sleckman, Barry P., Bassing, Craig H.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401341/
https://ncbi.nlm.nih.gov/pubmed/22730535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200829
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items