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Redundant and Non-Redundant Functions of ATM and H2AX in αβ T-Lineage Lymphocytes
The Ataxia Telangiectasia mutated (ATM) kinase and H2AX histone tumor suppressor proteins are each critical for maintenance of cellular genomic stability and suppression of lymphomas harboring clonal translocations. ATM is the predominant kinase that phosphorylates H2AX in chromatin around DNA doubl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401341/ https://ncbi.nlm.nih.gov/pubmed/22730535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200829 |
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