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Redundant and Non-Redundant Functions of ATM and H2AX in αβ T-Lineage Lymphocytes

The Ataxia Telangiectasia mutated (ATM) kinase and H2AX histone tumor suppressor proteins are each critical for maintenance of cellular genomic stability and suppression of lymphomas harboring clonal translocations. ATM is the predominant kinase that phosphorylates H2AX in chromatin around DNA doubl...

詳細記述

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書誌詳細
主要な著者: Yin, Bu, Lee, Baeck-Seung, Yang-Iott, Katherine S., Sleckman, Barry P., Bassing, Craig H.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401341/
https://ncbi.nlm.nih.gov/pubmed/22730535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200829
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