Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation

Lymphocyte antigen receptor gene assembly occurs through the process of V(D)J recombination, which is initiated when the RAG endonuclease introduces DNA DSBs at two recombining gene segments to form broken DNA coding end pairs and signal end pairs. These paired DNA ends are joined by proteins of the...

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Detalhes bibliográficos
Main Authors: Gapud, Eric J., Dorsett, Yair, Yin, Bu, Callen, Elsa, Bredemeyer, Andrea, Mahowald, Grace K., Omi, Kazuo Q., Walker, Laura M., Bednarski, Jeffrey J., McKinnon, Peter J., Bassing, Craig H., Nussenzweig, Andre, Sleckman, Barry P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033293/
https://ncbi.nlm.nih.gov/pubmed/21245316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013295108
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