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Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions
In 1988, the gene responsible for the autosomal recessive disease ataxia- telangiectasia (A-T) was localized to 11q22.3-23.1. It was eventually cloned in 1995. Many independent laboratories have since demonstrated that in replicating cells, ataxia telangiectasia mutated (ATM) is predominantly a nucl...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3709651/ https://ncbi.nlm.nih.gov/pubmed/23440242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-09-456897 |
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