Atm reactivation reverses ataxia telangiectasia phenotypes in vivo

Hereditary deficiencies in DNA damage signaling are invariably associated with cancer predisposition, immunodeficiency, radiation sensitivity, gonadal abnormalities, premature aging, and tissue degeneration. ATM kinase has been established as a central player in DNA double-strand break repair and it...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Di Siena, Sara, Campolo, Federica, Gimmelli, Roberto, Di Pietro, Chiara, Marazziti, Daniela, Dolci, Susanna, Lenzi, Andrea, Nussenzweig, Andre, Pellegrini, Manuela
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833483/
https://ncbi.nlm.nih.gov/pubmed/29472706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0357-8
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