Functional Intersection of ATM and DNA-Dependent Protein Kinase Catalytic Subunit in Coding End Joining during V(D)J Recombination

V(D)J recombination is initiated by the RAG endonuclease, which introduces DNA double-strand breaks (DSBs) at the border between two recombining gene segments, generating two hairpin-sealed coding ends and two blunt signal ends. ATM and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are s...

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Main Authors: Lee, Baeck-Seung, Gapud, Eric J., Zhang, Shichuan, Dorsett, Yair, Bredemeyer, Andrea, George, Rosmy, Callen, Elsa, Daniel, Jeremy A., Osipovich, Oleg, Oltz, Eugene M., Bassing, Craig H., Nussenzweig, Andre, Lees-Miller, Susan, Hammel, Michal, Chen, Benjamin P. C., Sleckman, Barry P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753869/
https://ncbi.nlm.nih.gov/pubmed/23836881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00308-13
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