MLKL requires the inositol phosphate code to execute necroptosis

Necroptosis is an important form of lytic cell death triggered by injury and infection, yet whether mixed lineage kinase domain-like (MLKL) is sufficient to execute this pathway is unknown. In a genetic selection for human cell mutants defective for MLKL-dependent necroptosis, we identified mutation...

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Bibliografski detalji
Izdano u:Mol Cell
Glavni autori: Dovey, Cole M., Diep, Jonathan, Clarke, Bradley P., Hale, Andrew T., McNamara, Dan E., Guo, Hongyan, Brown, Nathaniel W., Cao, Jennifer Yinuo, Grace, Christy R., Gough, Peter J., Bertin, John, Dixon, Scott J., Fiedler, Dorothea, Mocarski, Edward S., Kaiser, William J., Moldoveanu, Tudor, York, John D., Carette, Jan E.
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994928/
https://ncbi.nlm.nih.gov/pubmed/29883610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.05.010
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