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MLKL requires the inositol phosphate code to execute necroptosis
Necroptosis is an important form of lytic cell death triggered by injury and infection, yet whether mixed lineage kinase domain-like (MLKL) is sufficient to execute this pathway is unknown. In a genetic selection for human cell mutants defective for MLKL-dependent necroptosis, we identified mutation...
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| Izdano u: | Mol Cell |
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| Glavni autori: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5994928/ https://ncbi.nlm.nih.gov/pubmed/29883610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.05.010 |
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